As stated, load Minion Pro using the fontspec package. Something like the following might be adequate:<br><br style="font-family: courier new,monospace;"><div style="margin-left: 40px;"><span style="font-family: courier new,monospace;">\documentlcass{article}</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">\usepackage{fontspec}</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\setmainfont[Numbers={OldStyle,Proportional}]{Minion Pro}</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">\begin{document}</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">These 123 are oldstyle, proportional figures.</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">\addfontfeature{Numbers=Monospaced} These 123 are oldstyle, tabular figures.</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\end{document}</span><br>
</div><br>Or instead of adding (or changing) font features, create a new font family as Fr Michael shows.<br><br>Also note that you might receive erratic behaviour if you have different versions Minion Pro installed in different locations (e.g. in your TeX tree and in your system font folder). This method does not change the maths font.<br>
<br>If you have a lot of maths, you might find that PDFLaTeX and the MinionPro package actually produces better results. But if you really want to use XeLaTeX, then you should also use the mathspec and MnSymbol packages:<br>
<br><div style="margin-left: 40px;"><span style="font-family: courier new,monospace;">\documentclass{article}</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\usepackage[MnSymbol]{mathspec}</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">\setprimaryfont[Numbers={OldStyle,Proportional}]{Minion Pro}</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\setmathsfont[Set=Latin,Numbers={Monospaced,Lining}]{Minion Pro}</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">\setmathsfont[Set=Greek]{Minion Pro}</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\begin{documnt}</span><br style="font-family: courier new,monospace;">
<span style="font-family: courier new,monospace;">et cetera. \[ \sum_{i=1}^\infty a_n x^n \]</span><br style="font-family: courier new,monospace;"><span style="font-family: courier new,monospace;">\end{document}</span><br>
</div><br>(I didn't test the above examples because I don't have TeX installed at the moment.) <br><br>Andrew<br><br>