\documentclass[10pt]{article}

\usepackage{fontspec}


\begin{document}

Without selecting font:

\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, 
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,

After font selection:

\setmonofont{Latin Modern Mono}
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, 
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+, \verb+hyphenate+,
\end{document}
